The history of human coronaviruses began in 1965 when Tyrrell and Bynoe found that they could passage a virus named B814.
These viruses are associated with both upper and lower respiratory tract disease and are likely common human pathogens
Symptoms
Signs and symptoms of COVID-19 may appear two to 14 days after exposure and can include:
- Fever
- Cough
- Shortness of breath or difficulty breathing
Other symptoms can include:
- Tiredness
- Aches
- Runny nose
- Sore throat
The severity of COVID-19 symptoms can range from very mild to severe. Some people have no symptoms. People who are older or have existing chronic medical conditions, such as heart or lung disease or diabetes, may be at higher risk of serious illness. This is similar to what is seen with other respiratory illnesses, such as influenza.
Take steps to protect yourself
Clean your hands often
- Wash your hands often with soap and water for at least 20 seconds especially after you have been in a public place, or after blowing your nose, coughing, or sneezing.
Avoid close contact
- Avoid close contact with people who are sick
Take steps to protect others

Stay home if you’re sick
- Stay home if you are sick, except to get medical care.
Cover coughs and sneezes
- Cover your mouth and nose with a tissue when you cough or sneeze or use the inside of your elbow.
- Throw used tissues in the trash.
- Immediately wash your hands with soap and water for at least 20 seconds. If soap and water are not readily available, clean your hands with a hand sanitizer that contains at least 60% alcohol.
- wear face mask…